1. Anti-HMGCR antibody detection. Anti-HMGCR antibodies were measured by two ELISA tests (one home-made, one commercial) and confirmed by

HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase) is a Protein Coding gene. Diseases associated with HMGCR include Familial Hyperlipidemia and Sitosterolemia. Among its related pathways are Sterol Regulatory Element-Binding Proteins (SREBP) signalling and Regulation of cholesterol biosynthesis by SREBP (SREBF).

Storage Condition and Buffer: HMGCR Antibodies Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik2, also known as glutamate receptor 6, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. HMGCR Autoantibodies. Also known as: HMG; Statin associated myopathy; necrotising myopathy.

Hmgcr antibody

HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, 341 antibodies from 32 providers. Show Additional Columns. Antibody properties References Host Reactivity Antibody type Conjugate 2015-08-01 Monoclonal Anti-HMGCR antibody produced in mouse Prestige Antibodies ® Powered by Atlas Antibodies, clone CL0260, purified immunoglobulin, buffered aqueous glycerol solution : human: immunohistochemistry, western blot pricing 2016-10-01 Rabbit Polyclonal HMGCR antibody. Validated in WB, ICC/IF, IHC-P. Tested in Human, Mouse, Rat. Cited in 1 reference(s). Anti-HMGCR Antibody. 3-hydroxy-3-methylglutaryl-CoA reductase References (1) Recommended Applications Genetic validation in WB by siRNA knockdown.

Rabbit recombinant monoclonal HMGCR antibody [EPR1685(N)]. Validated in WB, IP and tested in Mouse, Rat, Human. Cited in 53 publication(s). Independently reviewed in 5 review(s).

performed using HMGCR, or both: a 2 x 2 factorial Mendelian rando- in PCSK9 and HMGCR and risk of cardiovascular antidrug-antibody formation with bococizumab. Celltypspecifik RNAi av Hmgcr med användning av DY-635 [NP] (siHMGCR) of endogenous HMGCR, anti-human HMGCR antibodies (Santa Cruz) were HMGCR.

Boster Bio Anti-HMGCR Antibody catalog # A00643-2. Tested in IP, WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100ul in Liquid form antibody.

Response The test result is given as negative or positive with a value. Reference value: Negative <20 U/mL, Positive ≥20 U/ mL. Anti-HMGCR antibodies represent a characteristic serological feature of statin-exposed and statin-unexposed patients with immune-mediated necrotizing myopathy (IMNM). We assessed anti-HMGCR antibodies in patients with suspected IMNM following statin exposure and patients with other autoimmune rheuma … Mouse monoclonal HMGCR antibody [CL0260].

Pronounced proximal muscle weakness is typical while lung involvement is less common. Antibody information for antibodies HPA008338 and CAB016797 used in analysis of ENSG00000113161 / HMGCR () Paraffin-embedded human fallopian tube tissue stained for HMGCR using ab242315 at 1/50 dilution in immunohistochemical analysis. Western blot - Anti-HMGCR antibody [CL0260] (ab242315) All lanes : Anti-HMGCR antibody [CL0260] (ab242315) at 1 µg/ml. Lane 1 : MCF7 (human breast adenocarcinoma cell line) whole cell lysate. 2020-08-13 · HMGCR Abs (3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase) are associated with necrotizing myopathy that is commonly related to statin exposure. Limitations This test was developed and its performance characteristics determined by LabCorp.
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As a single case report, the presented clinical and laboratory findings can only be considered hypothesis generating. It is unclear whether anti‐HMGCR IgG antibodies to 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are mainly associated with necrotizing autoimmune myopathy (NAM) in a subset of statin-treated patients.

doi: 10.1002/art.27572). Invitrogen Anti-HMGCR Polyclonal, Catalog # PA5-37367. Tested in Western Blot (WB), Immunocytochemistry (ICC) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody reacts with Human, Mouse, Rat samples.
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HMGCR antibody Rabbit Polyclonal from Proteintech validated in Immunohistochemistry (IHC), Immunofluorescence (IF),Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, mouse, rat samples. Cat.No. 13533-1-AP.

autoimmun myosit Inklusionskroppsmyosit NXP2- T1γ- SRP- HMGCR- cn1a- Anti-phospholipid antibodies may indicate phospholipid antibody syndrome.